480500-FS2025-0-Medicinal Inorganic Chemistry





Root number 480500
Semester FS2025
Type of course Lecture
Allocation to subject Chemistry
Type of exam Written exam
Title Medicinal Inorganic Chemistry
Description Medicinal inorganic chemistry is a relatively young, interdisciplinary research area that has grown primarily due to the success of cisplatin, a Pt-based anticancer drug developed in the late 1960s. Currently, metal complexes are used in many areas of medicine including anticancer and antimicrobial. The rational design of metal-based drugs is therefore a relatively new concept, facilitated by improvements in characterization and imaging techniques. During the lecture, it will be shown and emphasized that a metal complex that is administered is likely to be a prodrug that undergoes a transformation in vivo before reaching its target sites.
Elucidating the precise mechanisms of action of these new drugs is perhaps the most challenging
and complicated aspect of the research, because it requires drawing together knowledge concerning the reactivity of the metal complex.
During the lectures, using selected examples, we provide an overview of the uses of metal-based drugs in these diverse medical fields and, where appropriate, we guide the students to publications that provide a more in-depth analysis.

Relevant literature will be provided.
The book by FA Cotton & G. Wilkinson "Advanced-Inorganic-Chemistry" contains all the theoretical bases used in the course.
The website https://chem.libretexts.org/ contains a lot of useful information and courses in inorganic and organometallic chemistry.

Prerequisites: Bachelor’s degree in chemistry. Sufficient background in inorganic chemistry (lectures AC I & II at the DCBP).

Please register for this lecture through KSL/CTS in order to get access to the documents in ILIAS.
ILIAS-Link (Learning resource for course) Registrations are transmitted from CTS to ILIAS (no admission in ILIAS possible). ILIAS
Link to another web site
Lecturers Prof. Dr. Julien FurrerDCBP Gruppe Prof. Furrer 
ECTS 1.5
Recognition as optional course possible No
Grading 1 to 6
 
Dates Monday 13:15-15:00 Weekly
Thursday 13:15-15:00 Weekly
Thursday 10/4/2025 13:00-14:00
 
Rooms Seminarraum N213, Chemie, Biochemie und Pharmazie, DCBP
Hörsaal S481, Chemie, Biochemie und Pharmazie, DCBP
 
Students please consult the detailed view for complete information on dates, rooms and planned podcasts.