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Root number
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394632 |
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Semester
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HS2024 |
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Type of course
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Lecture |
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Allocation to subject
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Biomedical Engineering |
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Type of exam
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not defined |
| Title |
BioMicrofluidics |
| Description |
Auditors (Gasthörer) are not admitted to this course.
For questions on course and exam registration contact bme.artorg@unibe.ch.
Course Type: Lecture and Lab
Modules: Mandatory Courses / Major Module Biomechanics.
Selection Criteria: 1. Students with MM Biomechanics 2. Other BME students. 3. GCB students. 4. Other students.
Teaching assistants - lab:
- Dr. DeDe Man (kwun.man@unibe.ch)
- Negar Vahdani (negar.vahdani@unibe.ch)
Teaching assistant - exercises:
- Johannes Fehr (johannes.fehr@unibe.ch)
Course materials are regularly posted on Ilias (www.ilias.unibe.ch).
Attendance rules:
• Attendance at the Hand-on-BioMEMS training is mandatory.
• Attendance at the lectures is highly recommended.
Lab/Assignments:
Exercises and Lab (Hand-on-BioMEMS training mandatory)
Microfluidic project: theoretical project to be carried out during the semester (team of two students)
Exercises: 3-4 exercises are distributed at the end of each lecture. For questions please contact Johannes Fehr (johannes.fehr@students.unibe.ch).
Textbook(s) and other Reading Materials:
• Introduction to BioMEMS, Albert Folch, CRC Press, 2012.
• Theoretical Microfluidics, Henrik Bruus, Oxford University Press, 2008.
• Microfluidics and Multi Organs on Chip, Springer, 2022.
Description:
In the first part of the course, the students will learn which effects govern the transport of small volumes of liquid in confined microchannels and microwells. At the micro- and nanoscale, microfluidic phenomena, such as surface tension, electrokinetic effects, molecular diffusion, heat transfer have a tremendous impact that opens novel opportunities for basic, clinical research as well as for commercial applications.
In the second part of the course, a number of microfluidic systems will be presented, with an emphasis on lab-on-chips and organs-on-chip. Lab-on-chip devices are miniaturized systems that integrate multiple laboratory functions on a single chip, allowing for complex analyses to be performed with small sample volumes. They enable rapid and efficient chemical, biological, and physical processes, making them valuable for diagnostics, drug development, and research. Organs-on-chips are advanced in-vitro systems, in which cells are cultured in an environment that resembles their native milieu. Such systems have dimensions that are similar to mammalian cells and thus are ideal to reproduce specific aspects of the cellular environment, such as the three-dimensional architecture of a tissue, the continuous or intermittent perfusion of cells, and/or the mechanical strain induced by the breathing movements. Organs-on-chip are being implemented in the preclinical field, in particular in the drug discovery process, where new drug candidates are tested for their toxicity (potential side effects) and efficacy. They are also seen as an alternative to animal experiments and will become key tools in personalized and precision medicine. |
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ILIAS-Link (Learning resource for course)
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Registrations are transmitted from CTS to ILIAS (no admission in ILIAS possible).
ILIAS
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Link to another web site
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Further information for this course
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| Lecturers |
Prof. Dr.
Olivier Thierry Guenat, ARTORG Center - Organs-on-Chip Technologies (OOC) ✉
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ECTS
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3 |
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Recognition as optional course possible
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No |
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Grading
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1 to 6 |
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| Dates |
Wednesday 13:15-15:00 Weekly
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Thursday 24/10/2024 12:15-16:00
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Thursday 7/11/2024 12:15-16:00
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Monday 25/11/2024 10:15-12:00
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Wednesday 29/1/2025 09:00-17:00
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| Rooms |
Hörraum B 101, Institutsgebäude vonRoll
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| External rooms |
ARTORG Center, Floor B and C, Murtenstrasse 50
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ARTORG Center, Room F-502, Murtenstrasse 50
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Hörsaalgebäude vonRoll, Room 103, Fabrikstrasse 6
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Institutsgebäude vonRoll, Room C302, Fabrikstrasse 8ddd
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| Students please consult the detailed view for complete information on dates, rooms and planned podcasts. |
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